What is a Indoline (C₈H₉N) ?

Indoline (C₈H₉N) is a heterocyclic aromatic amine consisting of a benzene ring fused with a five-membered nitrogen-containing ring. It is a partially hydrogenated derivative of indole, where the double bond in the pyrrole-like ring is saturated. Indoline is a colorless to pale yellow liquid with a distinctive odor and is a key intermediate in organic synthesis.

It is widely used in the manufacture of dyes, pharmaceuticals, agrochemicals, liquid crystals, and functional materials. In medicinal chemistry, the indoline structure serves as a core in many bioactive compounds with reported antibacterial, anticancer, and anti-inflammatory properties.

Indoline exhibits both aromatic and amine reactivity, undergoing alkylation, acylation, and oxidation. It is also useful in constructing complex molecules through hydrogenation or halogenation. Caution is needed due to its volatility and potential toxicity.

※Includes information on some trading companies