What is a Sulfonamide (R-SO2-NH2) ?

Sulfonamide (R-SO2-NH2) refers to a group of organic compounds containing a sulfonyl group (–SO2–) and an amino group (–NH2). Sulfonamides are widely used in pharmaceuticals, industrial products, and pesticides. Particularly, sulfonamide antibiotics have been used in medical treatments since the 1940s, where they inhibit bacterial growth by blocking the synthesis of folic acid, an essential component for bacteria. They are still used in the treatment of certain infections, such as urinary tract infections and respiratory infections. However, sulfonamides may cause allergic reactions and side effects, such as skin rashes and fever, so they should be used with caution, especially in patients with a history of allergies. Sulfonamides are also used in agriculture as pesticides and in the production of industrial products and electronic devices.

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