What is a Sodium periodate (NaIO₄)?

Sodium periodate (NaIO₄) is the sodium salt of periodic acid and is a strong oxidizing agent. It typically appears as colorless or white crystalline solid or crystalline powder and is highly soluble in water. Sodium periodate plays a crucial role in many chemical processes, especially in organic chemistry. This compound is widely used in oxidation reactions, including alcohol oxidation, the ring-opening of epoxides, and the oxidation of polysaccharides and deoxyribonucleotides. Sodium periodate’s strong oxidative power facilitates a wide range of chemical reactions by altering the oxidation state of molecules.

It is also used in redox reactions and as a reagent in organic synthesis, often for selective oxidation of specific carbon-hydrogen bonds. Due to its strong oxidizing properties, sodium periodate must be handled with caution. It should be kept away from moisture and appropriate protective equipment should be used during handling to avoid direct contact.

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