Hypoxanthine / List of 0 manufacturers
What is a Hypoxanthine?
Hypoxanthine is a purine derivative with the chemical formula C₅H₄N₄O. It plays an important role as an intermediate in the metabolism of nucleic acids (DNA and RNA). It is structurally similar to adenine and guanine and occurs naturally in the degradation pathway of nucleotides.
Key roles and characteristics:
✅ Metabolic intermediate:
Formed during the breakdown of adenine, which is further oxidized to xanthine and then to uric acid.
✅ Base analog in DNA:
In experimental settings, hypoxanthine can be incorporated into DNA, possibly causing base mismatches due to improper pairing.
✅ Cell culture supplement:
Used in HAT (hypoxanthine-aminopterin-thymidine) medium to select certain genetically modified cells.
Physiological relevance:
✅ Involved in purine metabolism in organs such as the liver and kidneys.
✅ As a precursor to uric acid, it is associated with gout and other uric acid-related disorders.
✅ Also found in meats and seafood, contributing to flavor and freshness assessment, especially in fish.
Manufacture list of Hypoxanthine
※Includes information on some trading companies
